Dr. Jean Vivien Mombouli
About Dr. Jean Vivien Mombouli
Jean Vivien Mombouli, PhD
Directeur du Departement de la Recherche et de la Production
Laboratoire Nationale de Sante Publique
Brazzaville, Republic of Congo
Dr. Jean-Vivien Mombouli is Director of the Department of Research
and Production, National Laboratory for Public Health of Congo and
Assistant Professor at Marien Ngouabi University of Brazzaville,
Congo. Dr. Mombouli received his PhD in Molecular Physiology and
Pharmacology from the University of Poiters, France. He has written
over 22 original research articles and 6 book chapters.
Dr. Mombouli’s present aim of study is the pathophysiological
modulation of blood vessel function induced by infectious agents
in Malaria, HIV-AIDS, Human African Trypanosomiasis, Schistosomiasis
and Ebola virus. Blood borne microbial pathogens cause pro-inflammatory
reactions that impact negatively the perfusion of organs with nutritious
elements and/or tissue cleansing by blood of metabolism by-products.
The resulting impairment of blood flow causes some stress that may
contribute to observed morbidity, and in some instances to death.
Blood borne pathogens alter blood vessel function (control of vessel
caliber and blood fluidity) in ways that support our overall working
hypothesis that certain drugs developed for cardiovascular diseases
may be of great help in the adjuvant symptomatic treatment of severe
infectious diseases. Scientific literature supports in theory such
a role for cardiovascular drugs in the treatment of Ebola Hemorrhagic
fever and malaria.
The National Public Health Laboratory aims to establish a map of
health risks that would cover the Republic of Congo. Construction
of both resident and mobile laboratory capacity to be able to monitor
routinely emergence of acute disease outbreaks such as Ebola viral
epidemics, or assess parametric changes in perennial epidemics such
as malaria parasite drug-resistance patterns.
To these ends, cooperation in remote areas with community-based
organizations such as the Congolese Red Cross or conservation organizations
is warranted to compensate for lack of personnel.